MeCheck  /  GALEAS Bladder

A urine test for bladder cancer.

Not currently available

GALEAS™ Bladder looks for DNA changes shed by bladder tumours into urine. It is collected at home, analysed by targeted sequencing, and returns a simple positive or negative result. MeCheck previously offered GALEAS Bladder, but it is not currently available. Register your interest and we will let you know if it returns.

Register interest Make an enquiry

Seen blood in your urine? Do not wait for a test from us. Visible blood in the urine needs prompt assessment — contact your GP, or call NHS 111.

How it works

You collect a urine sample at home in a barcoded collection device and post it to the laboratory. DNA is extracted from the cells in the sample and an ultra-sensitive next-generation sequencing panel checks it for mutations found in bladder cancer — the panel covers changes present in over 96% of bladder cancers. Results are interpreted by the GALEAS software and reported as positive or negative.

It is designed for people with blood in their urine (haematuria), most of whom turn out not to have bladder cancer. A positive result means you should have a cystoscopy; a negative result is reassuring but does not rule cancer out completely.

The detail

SampleUrine, collected at home
MethodTargeted next-generation sequencing of tumour DNA
ResultPositive or negative for likely bladder cancer
SensitivityOver 90% overall (manufacturer reported)
Specificity86% (manufacturer reported)
Validation710 urine samples from three UK clinical cohorts
Developed byNonacus, with the University of Birmingham
RegulatoryUKCA marked

Performance figures are from the manufacturer, Nonacus Ltd. A screening result is not a diagnosis and does not replace assessment by a doctor.

Register interest or enquire

GALEAS Bladder is not currently available through MeCheck. Leave your details and we will let you know if that changes, or answer your question. We aim to reply within two working days. Please do not include details of symptoms or your medical history.